Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein

OBJECTIVE: Cholesteryl ester transfer protein (CETP) plays a central role in the metabolism of high-density lipoprotein particles. Therefore, we searched for new drugs that bind to CETP and modulate its activity. METHODS: A preliminary pharmacophore-based parallel screening approach indicated that l...

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Detalhes bibliográficos
Main Authors: Duwensee, Kristina, Schwaiger, Stefan, Tancevski, Ivan, Eller, Kathrin, van Eck, Miranda, Markt, Patrick, Linder, Tobias, Stanzl, Ursula, Ritsch, Andreas, Patsch, Josef R., Schuster, Daniela, Stuppner, Hermann, Bernhard, David, Eller, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212649/
https://ncbi.nlm.nih.gov/pubmed/21820657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2011.07.023
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