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Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington’s Disease

Within the past decade, there has been increasing interest in the role of tryptophan (Trp) metabolites and the kynurenine pathway (KP) in diseases of the brain such as Huntington’s disease (HD). Evidence is accumulating to suggest that this pathway is imbalanced in neurologic disease states. The KP...

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Detalhes bibliográficos
Publicado no:J Huntingtons Dis
Principais autores: Mazarei, Gelareh, Leavitt, Blair R.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923717/
https://ncbi.nlm.nih.gov/pubmed/26397892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-159003
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