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Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium

Tissue organoids are a promising technology that may accelerate development of the societal and NIH mandate for precision medicine. Here we describe a robust and simple method for generating cerebral organoids (cOrgs) from human pluripotent stem cells by using a chemically defined hydrogel material...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Lindborg, Beth A., Brekke, John H., Vegoe, Amanda L., Ulrich, Connor B., Haider, Kerri T., Subramaniam, Sandhya, Venhuizen, Scott L., Eide, Cindy R., Orchard, Paul J., Chen, Weili, Wang, Qi, Pelaez, Francisco, Scott, Carolyn M., Kokkoli, Efrosini, Keirstead, Susan A., Dutton, James R., Tolar, Jakub, O’Brien, Timothy D.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922855/
https://ncbi.nlm.nih.gov/pubmed/27177577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0305
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