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Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids
Genomic studies are rapidly identifying genetic alterations in human cancer, but functional validation of such alterations has been slow. Here, using human prostate cancer as a model, we have assessed the feasibility of engineering defined genetic alterations in well-known cancer driver genes to tra...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584247/ https://ncbi.nlm.nih.gov/pubmed/28881646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17230 |
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