Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque

Delta-5 desaturase (D5D) and delta-6 desaturase (D6D), encoded by fatty acid desaturase 1 (FADS1) and FADS2 genes, respectively, are enzymes in the synthetic pathways for ω3, ω6, and ω9 polyunsaturated fatty acids (PUFAs). Although PUFAs appear to be involved in mammalian metabolic pathways, the phy...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes Metab Syndr Obes
Prif Awduron: Powell, David R, Gay, Jason P, Smith, Melinda, Wilganowski, Nathaniel, Harris, Angela, Holland, Autumn, Reyes, Maricela, Kirkham, Laura, Kirkpatrick, Laura L, Zambrowicz, Brian, Hansen, Gwenn, Platt, Kenneth A, van Sligtenhorst, Isaac, Ding, Zhi-Ming, Desai, Urvi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922822/
https://ncbi.nlm.nih.gov/pubmed/27382320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S106653
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