Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque

Delta-5 desaturase (D5D) and delta-6 desaturase (D6D), encoded by fatty acid desaturase 1 (FADS1) and FADS2 genes, respectively, are enzymes in the synthetic pathways for ω3, ω6, and ω9 polyunsaturated fatty acids (PUFAs). Although PUFAs appear to be involved in mammalian metabolic pathways, the phy...

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Dades bibliogràfiques
Publicat a:Diabetes Metab Syndr Obes
Autors principals: Powell, David R, Gay, Jason P, Smith, Melinda, Wilganowski, Nathaniel, Harris, Angela, Holland, Autumn, Reyes, Maricela, Kirkham, Laura, Kirkpatrick, Laura L, Zambrowicz, Brian, Hansen, Gwenn, Platt, Kenneth A, van Sligtenhorst, Isaac, Ding, Zhi-Ming, Desai, Urvi
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922822/
https://ncbi.nlm.nih.gov/pubmed/27382320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S106653
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