Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque

Delta-5 desaturase (D5D) and delta-6 desaturase (D6D), encoded by fatty acid desaturase 1 (FADS1) and FADS2 genes, respectively, are enzymes in the synthetic pathways for ω3, ω6, and ω9 polyunsaturated fatty acids (PUFAs). Although PUFAs appear to be involved in mammalian metabolic pathways, the phy...

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Bibliografski detalji
Izdano u:Diabetes Metab Syndr Obes
Glavni autori: Powell, David R, Gay, Jason P, Smith, Melinda, Wilganowski, Nathaniel, Harris, Angela, Holland, Autumn, Reyes, Maricela, Kirkham, Laura, Kirkpatrick, Laura L, Zambrowicz, Brian, Hansen, Gwenn, Platt, Kenneth A, van Sligtenhorst, Isaac, Ding, Zhi-Ming, Desai, Urvi
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922822/
https://ncbi.nlm.nih.gov/pubmed/27382320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S106653
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