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The Role of Putative Phosphatidylserine-Interactive Residues of Tissue Factor on Its Coagulant Activity at the Cell Surface

Exposure of phosphatidylserine (PS) on the outer leaflet of the cell membrane is thought to play a critical role in tissue factor (TF) decryption. Recent molecular dynamics simulation studies suggested that the TF ectodomain may directly interact with PS. To investigate the potential role of TF dire...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ansari, Shabbir A., Pendurthi, Usha R., Sen, Prosenjit, Rao, L. Vijaya Mohan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922585/
https://ncbi.nlm.nih.gov/pubmed/27348126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158377
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