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Factor VIIa Interaction with Tissue Factor and Endothelial Cell Protein C Receptor on Cell Surfaces

Factor VIIa (FVIIa) is the enzyme that triggers activation of the clotting cascade that eventually leads to fibrin deposition and platelet activation. Association of FVIIa with its cellular receptor, tissue factor (TF), which greatly increases FVIIa enzymatic activity, is essential for the effective...

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Autors principals: Pendurthi, Usha R., Vijaya Mohan Rao, L.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491344/
https://ncbi.nlm.nih.gov/pubmed/18544419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2008.03.014
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