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Factor VIIa Interaction with Tissue Factor and Endothelial Cell Protein C Receptor on Cell Surfaces

Factor VIIa (FVIIa) is the enzyme that triggers activation of the clotting cascade that eventually leads to fibrin deposition and platelet activation. Association of FVIIa with its cellular receptor, tissue factor (TF), which greatly increases FVIIa enzymatic activity, is essential for the effective...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pendurthi, Usha R., Vijaya Mohan Rao, L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491344/
https://ncbi.nlm.nih.gov/pubmed/18544419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2008.03.014
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