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Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B(1) Toxicity

The transcription factor Nrf2 (NF-E2-related-factor 2) regulates a battery of antioxidative stress-response genes and detoxication genes, and Nrf2 knockout lines of mice have been contributing critically to the clarification of roles that Nrf2 plays for cell protection. However, there are apparent l...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Taguchi, Keiko, Takaku, Misaki, Egner, Patricia A., Morita, Masanobu, Kaneko, Takehito, Mashimo, Tomoji, Kensler, Thomas W., Yamamoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922541/
https://ncbi.nlm.nih.gov/pubmed/27071940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw065
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