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Simple knockout by electroporation of engineered endonucleases into intact rat embryos
Engineered endonucleases, such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system, provide a powerful approach for genome editing in animals. However, the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180828/ https://ncbi.nlm.nih.gov/pubmed/25269785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06382 |
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