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Development of Diubiquitin‐Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

Deubiquitinating enzymes (DUBs) are proteases that fulfill crucial roles in the ubiquitin (Ub) system, by deconjugation of Ub from its targets and disassembly of polyUb chains. The specificity of a DUB towards one of the polyUb chain linkages largely determines the ultimate signaling function. We pr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Chembiochem
Päätekijät: Geurink, Paul P., van Tol, Bianca D. M., van Dalen, Duco, Brundel, Paul J. G., Mevissen, Tycho E. T., Pruneda, Jonathan N., Elliott, Paul R., van Tilburg, Gabriëlle B. A., Komander, David, Ovaa, Huib
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922411/
https://ncbi.nlm.nih.gov/pubmed/26996281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600017
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