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Peroxiredoxin 6 as an antioxidant enzyme: protection of lung alveolar epithelial type II cells from H(2)O(2)-induced oxidative stress

We evaluated the anti-oxidant role of peroxiredoxin 6 (Prdx6) in primary lung alveolar epithelial type II cells (AEC II) that were isolated from wild-type, Prdx6−/−, or Prdx6 transgenic overexpressing (Tg) mice and exposed to H(2)O(2) at 50µM - 500µM for 1-24 hours. Expression of Prdx6 in Tg AEC II...

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Publicat a:J Cell Biochem
Autors principals: Wang, Yan, Feinstein, Sheldon I., Fisher, Aron B.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922305/
https://ncbi.nlm.nih.gov/pubmed/18260127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21703
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