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Elucidation of cladofulvin biosynthesis reveals a cytochrome P450 monooxygenase required for anthraquinone dimerization

Anthraquinones are a large family of secondary metabolites (SMs) that are extensively studied for their diverse biological activities. These activities are determined by functional group decorations and the formation of dimers from anthraquinone monomers. Despite their numerous medicinal qualities,...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Griffiths, Scott, Mesarich, Carl H., Saccomanno, Benedetta, Vaisberg, Abraham, De Wit, Pierre J. G. M., Cox, Russell, Collemare, Jérôme
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922171/
https://ncbi.nlm.nih.gov/pubmed/27274078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603528113
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