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Lack of AKT in adipocytes causes severe lipodystrophy

OBJECTIVE: Adipose depot mass is tightly regulated to maintain energy homeostasis. AKT is a critical kinase in the insulin-signaling cascade that is required for the process of adipogenesis in vitro. However, the role of AKT in the maintenance and/or function of mature adipocytes in vivo had not bee...

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Publicado en:Mol Metab
Main Authors: Shearin, Abigail L., Monks, Bobby R., Seale, Patrick, Birnbaum, Morris J.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921941/
https://ncbi.nlm.nih.gov/pubmed/27408773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.05.006
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