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A Role for Nuclear Actin in HDAC 1 and 2 Regulation

Class I histone deacetylases (HDACs) are known to remove acetyl groups from histone tails. This liberates positive charges on the histone tail and allows for tighter winding of DNA, preventing transcription factor binding and gene activation. Although the functions of HDAC proteins are becoming appa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Serebryannyy, Leonid A., Cruz, Christina M., de Lanerolle, Primal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921920/
https://ncbi.nlm.nih.gov/pubmed/27345839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28460
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