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Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin

α-Catenin is an F-actin-binding protein widely recognized for its role in cell–cell adhesion. However, a growing body of literature indicates that α-catenin is also a nuclear protein. In this study, we show that α-catenin is able to modulate the sensitivity of cells to DNA damage and toxicity. Furth...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Serebryannyy, Leonid A., Yemelyanov, Alex, Gottardi, Cara J., de Lanerolle, Primal
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450192/
https://ncbi.nlm.nih.gov/pubmed/28348105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.199893
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