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A Role for Nuclear Actin in HDAC 1 and 2 Regulation

Class I histone deacetylases (HDACs) are known to remove acetyl groups from histone tails. This liberates positive charges on the histone tail and allows for tighter winding of DNA, preventing transcription factor binding and gene activation. Although the functions of HDAC proteins are becoming appa...

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Foilsithe in:Sci Rep
Main Authors: Serebryannyy, Leonid A., Cruz, Christina M., de Lanerolle, Primal
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921920/
https://ncbi.nlm.nih.gov/pubmed/27345839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28460
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