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CD138 and CD31 Double-Positive Cells Comprise the Functional Antibody-Secreting Plasma Cell Compartment in Primate Bone Marrow

Plasma cells (PCs) are defined as terminally differentiated B cells that secrete large amounts of immunoglobulin (Ig). PCs that reside in the bone marrow (BM) are responsible for maintaining long-term antibody (Ab) responses after infection and vaccination, while PCs present in the blood are general...

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Publicat a:Front Immunol
Autors principals: Martinez-Murillo, Paola, Pramanik, Lotta, Sundling, Christopher, Hultenby, Kjell, Wretenberg, Per, Spångberg, Mats, Karlsson Hedestam, Gunilla B.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921460/
https://ncbi.nlm.nih.gov/pubmed/27446073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00242
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