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Genetic Enhancement of Limb Defects in a Mouse Model of Cornelia de Lange Syndrome

Cornelia de Lange Syndrome (CdLS) is characterized by a wide variety of structural and functional abnormalities in almost every organ system of the body. CdLS is now known to be caused by mutations that disrupt the function of the cohesin complex or its regulators, and studies of animal models and c...

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Detalhes bibliográficos
Publicado no:Am J Med Genet C Semin Med Genet
Main Authors: LOPEZ-BURKS, MARTHA E., SANTOS, ROSAYSELA, KAWAUCHI, SHIMAKO, CALOF, ANNE L., LANDER, ARTHUR D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921392/
https://ncbi.nlm.nih.gov/pubmed/27120109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.c.31491
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