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Alpha-CENTAURI: assessing novel centromeric repeat sequence variation with long read sequencing

Motivation: Long arrays of near-identical tandem repeats are a common feature of centromeric and subtelomeric regions in complex genomes. These sequences present a source of repeat structure diversity that is commonly ignored by standard genomic tools. Unlike reads shorter than the underlying repeat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Sevim, Volkan, Bashir, Ali, Chin, Chen-Shan, Miga, Karen H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920115/
https://ncbi.nlm.nih.gov/pubmed/27153570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw101
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