Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II‐mediated hypertension

BACKGROUND AND PURPOSE: NO deficiency and oxidative stress are crucially involved in the development or progression of cardiovascular disease, including hypertension and stroke. We have previously demonstrated that acute treatment with the newly discovered organic nitrate, 2‐nitrate‐1,3‐dibuthoxypro...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Porpino, Suênia K P, Zollbrecht, Christa, Peleli, Maria, Montenegro, Marcelo F, Brandão, Maria C R, Athayde‐Filho, Petrônio F, França‐Silva, Maria S, Larsson, Erik, Lundberg, Jon O, Weitzberg, Eddie, Persson, Erik G, Braga, Valdir A, Carlström, Mattias
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919584/
https://ncbi.nlm.nih.gov/pubmed/27160064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13511
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