In adenosine A(2B) knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver

Rationale: Accumulating studies suggest that nitric oxide (NO) deficiency and oxidative stress are central pathological mechanisms in type 2 diabetes (T2D). Recent findings demonstrate therapeutic effects by boosting the nitrate-nitrite-NO pathway, which is an alternative pathway for NO formation. T...

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Pubblicato in:Front Physiol
Autori principali: Peleli, Maria, Hezel, Michael, Zollbrecht, Christa, Persson, A. Erik G., Lundberg, Jon O., Weitzberg, Eddie, Fredholm, Bertil B., Carlström, Mattias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528163/
https://ncbi.nlm.nih.gov/pubmed/26300787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00222
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