Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II‐mediated hypertension

BACKGROUND AND PURPOSE: NO deficiency and oxidative stress are crucially involved in the development or progression of cardiovascular disease, including hypertension and stroke. We have previously demonstrated that acute treatment with the newly discovered organic nitrate, 2‐nitrate‐1,3‐dibuthoxypro...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Porpino, Suênia K P, Zollbrecht, Christa, Peleli, Maria, Montenegro, Marcelo F, Brandão, Maria C R, Athayde‐Filho, Petrônio F, França‐Silva, Maria S, Larsson, Erik, Lundberg, Jon O, Weitzberg, Eddie, Persson, Erik G, Braga, Valdir A, Carlström, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919584/
https://ncbi.nlm.nih.gov/pubmed/27160064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13511
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