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Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus
BACKGROUND AND PURPOSE: Previous findings suggest that the growth and differentiation factor midkine (Mdk) is a negative regulator of osteoblast activity and bone formation, thereby raising the possibility that a specific Mdk antagonist might improve bone formation during fracture healing. EXPERIMEN...
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Pubblicato in: | Br J Pharmacol |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
John Wiley and Sons Inc.
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919577/ https://ncbi.nlm.nih.gov/pubmed/27111560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13503 |
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