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Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus

BACKGROUND AND PURPOSE: Previous findings suggest that the growth and differentiation factor midkine (Mdk) is a negative regulator of osteoblast activity and bone formation, thereby raising the possibility that a specific Mdk antagonist might improve bone formation during fracture healing. EXPERIMEN...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Haffner‐Luntzer, Melanie, Heilmann, Aline, Rapp, Anna Elise, Roessler, Robin, Schinke, Thorsten, Amling, Michael, Ignatius, Anita, Liedert, Astrid
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919577/
https://ncbi.nlm.nih.gov/pubmed/27111560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13503
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