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Hyperglycemic Conditions Prime Cells for RIP1-dependent Necroptosis

Necroptosis is a RIP1-dependent programmed cell death (PCD) pathway that is distinct from apoptosis. Downstream effector pathways of necroptosis include formation of advanced glycation end products (AGEs) and reactive oxygen species (ROS), both of which depend on glycolysis. This suggests that incre...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: LaRocca, Timothy J., Sosunov, Sergey A., Shakerley, Nicole L., Ten, Vadim S., Ratner, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919457/
https://ncbi.nlm.nih.gov/pubmed/27129772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.716027
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