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Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin

Abnormalities in parvalbumin (PV)-expressing interneurons cause neurodevelopmental disorders such as epilepsy, autism, and schizophrenia. Unlike other types of neurons that can be efficiently differentiated from pluripotent stem cells, PV neurons were minimally generated using a conventional differe...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Shi, Zixiao, Zhang, Juan, Chen, Shuangquan, Li, Yanxin, Lei, Xuepei, Qiao, Huimin, Zhu, Qianwen, Hu, Baoyang, Zhou, Qi, Jiao, Jianwei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919442/
https://ncbi.nlm.nih.gov/pubmed/27137935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709808
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