Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin

Abnormalities in parvalbumin (PV)-expressing interneurons cause neurodevelopmental disorders such as epilepsy, autism, and schizophrenia. Unlike other types of neurons that can be efficiently differentiated from pluripotent stem cells, PV neurons were minimally generated using a conventional differe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Shi, Zixiao, Zhang, Juan, Chen, Shuangquan, Li, Yanxin, Lei, Xuepei, Qiao, Huimin, Zhu, Qianwen, Hu, Baoyang, Zhou, Qi, Jiao, Jianwei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919442/
https://ncbi.nlm.nih.gov/pubmed/27137935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709808
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg