Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation

Using affinity purification MS approaches, we have identified a novel role for casein kinase II (CKII) in the modification of the polymerase associated factor complex (PAF-C). Our data indicate that the facilitates chromatin transcription complex (FACT) interacts with CKII and may facilitate PAF com...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bedard, Lynn Glowczewski, Dronamraju, Raghuvar, Kerschner, Jenny L., Hunter, Gerald O., Axley, Elizabeth DeVlieger, Boyd, Asha K., Strahl, Brian D., Mosley, Amber L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919428/
https://ncbi.nlm.nih.gov/pubmed/27143358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.727735
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