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Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription
Spt6 is an essential histone chaperone that mediates nucleosome reassembly during gene transcription. Spt6 also associates with RNA polymerase II (RNAPII) via a tandem Src2 homology domain. However, the significance of Spt6-RNAPII interaction is not well understood. Here, we show that Spt6 recruitme...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6323640/ https://ncbi.nlm.nih.gov/pubmed/29932900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.020 |
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