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Novel Clostridium difficile Anti-Toxin (TcdA and TcdB) Humanized Monoclonal Antibodies Demonstrate In Vitro Neutralization across a Broad Spectrum of Clinical Strains and In Vivo Potency in a Hamster Spore Challenge Model

Clostridium difficile (C. difficile) infection (CDI) is the main cause of nosocomial antibiotic-associated colitis and increased incidence of community-associated diarrhea in industrialized countries. At present, the primary treatment of CDI is antibiotic administration, which is effective but often...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রকাশিত:PLoS One
প্রধান লেখক: Qiu, Hongyu, Cassan, Robyn, Johnstone, Darrell, Han, Xiaobing, Joyee, Antony George, McQuoid, Monica, Masi, Andrea, Merluza, John, Hrehorak, Bryce, Reid, Ross, Kennedy, Kieron, Tighe, Bonnie, Rak, Carla, Leonhardt, Melanie, Dupas, Brian, Saward, Laura, Berry, Jody D., Nykiforuk, Cory L.
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: Public Library of Science 2016
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919053/
https://ncbi.nlm.nih.gov/pubmed/27336843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157970
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