MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

MUC16, a heavily glycosylated type-I transmembrane mucin is overexpressed in several cancers including pancreatic ductal adenocarcinoma (PDAC). Previously, we have shown that MUC16 is significantly overexpressed in human PDAC tissues. However, the functional consequences and its role in PDAC is poor...

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Dettagli Bibliografici
Pubblicato in:Genes Cancer
Autori principali: Muniyan, Sakthivel, Haridas, Dhanya, Chugh, Seema, Rachagani, Satyanarayana, Lakshmanan, Imayavaramban, Gupta, Suprit, Seshacharyulu, Parthasarathy, Smith, Lynette M., Ponnusamy, Moorthy P., Batra, Surinder K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918949/
https://ncbi.nlm.nih.gov/pubmed/27382435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.104
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