MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

MUC16, a heavily glycosylated type-I transmembrane mucin is overexpressed in several cancers including pancreatic ductal adenocarcinoma (PDAC). Previously, we have shown that MUC16 is significantly overexpressed in human PDAC tissues. However, the functional consequences and its role in PDAC is poor...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Cancer
Hauptverfasser: Muniyan, Sakthivel, Haridas, Dhanya, Chugh, Seema, Rachagani, Satyanarayana, Lakshmanan, Imayavaramban, Gupta, Suprit, Seshacharyulu, Parthasarathy, Smith, Lynette M., Ponnusamy, Moorthy P., Batra, Surinder K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918949/
https://ncbi.nlm.nih.gov/pubmed/27382435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.104
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