MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

MUC16, a heavily glycosylated type-I transmembrane mucin is overexpressed in several cancers including pancreatic ductal adenocarcinoma (PDAC). Previously, we have shown that MUC16 is significantly overexpressed in human PDAC tissues. However, the functional consequences and its role in PDAC is poor...

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Vydáno v:Genes Cancer
Hlavní autoři: Muniyan, Sakthivel, Haridas, Dhanya, Chugh, Seema, Rachagani, Satyanarayana, Lakshmanan, Imayavaramban, Gupta, Suprit, Seshacharyulu, Parthasarathy, Smith, Lynette M., Ponnusamy, Moorthy P., Batra, Surinder K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918949/
https://ncbi.nlm.nih.gov/pubmed/27382435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.104
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