MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

MUC16, a heavily glycosylated type-I transmembrane mucin is overexpressed in several cancers including pancreatic ductal adenocarcinoma (PDAC). Previously, we have shown that MUC16 is significantly overexpressed in human PDAC tissues. However, the functional consequences and its role in PDAC is poor...

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Dades bibliogràfiques
Publicat a:Genes Cancer
Autors principals: Muniyan, Sakthivel, Haridas, Dhanya, Chugh, Seema, Rachagani, Satyanarayana, Lakshmanan, Imayavaramban, Gupta, Suprit, Seshacharyulu, Parthasarathy, Smith, Lynette M., Ponnusamy, Moorthy P., Batra, Surinder K.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918949/
https://ncbi.nlm.nih.gov/pubmed/27382435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.104
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