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Notch signaling represses hypoxia-inducible factor-1α-induced activation of Wnt/β-catenin signaling in osteoblasts under cobalt-mimicked hypoxia

The modification of Wnt and Notch signaling pathways by hypoxia, and its association with osteoblast proliferation and apoptosis remain to be fully elucidated. To investigate Wnt-Notch crosstalk, and its role in hypoxia-induced osteoblast proliferation and apoptosis regulation, the present study inv...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: LI, CHEN-TIAN, LIU, JIAN-XIU, YU, BO, LIU, RUI, DONG, CHAO, LI, SONG-JIAN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918618/
https://ncbi.nlm.nih.gov/pubmed/27220406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5324
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