SDF-1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF-κB pathway

Intervertebral disc degeneration (IVDD) is a major cause of lower back pain, and increased cell apoptosis is a key characteristic of IVDD. The present study aimed to investigate the effects and mechanism of the stromal cell-derived factor-1 (SDF-1)/C-X-C motif chemokine receptor 4 (CXCR4) axis on ap...

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Publicado en:Mol Med Rep
Autores principales: LIU, ZONGCHAO, MA, CHUAN, SHEN, JIELIANG, WANG, DAWU, HAO, JIE, HU, ZHENMING
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2016
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918601/
https://ncbi.nlm.nih.gov/pubmed/27220474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5341
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