Duhuo Jisheng Decoction inhibits SDF-1-induced inflammation and matrix degradation in human degenerative nucleus pulposus cells in vitro through the CXCR4/NF-κB pathway

Lower back pain (LBP) is the most common disease in orthopedic clinics world-wide. A classic Fangji of traditional Chinese medicine, Duhuo Jisheng Decoction (DHJSD), has been proven clinically effective for LBP but its therapeutic mechanisms remain unclear. We hypothesized that DHJSD might relieve L...

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Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Liu, Zong-chao, Wang, Zhen-long, Huang, Chen-yi, Fu, Zhi-jiang, Liu, Yong, Wei, Zhang-chao, Liu, Shi-gui, Ma, Chuan, Shen, Jie-liang, Duan, Dayue Darrel
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256264/
https://ncbi.nlm.nih.gov/pubmed/29795361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2018.36
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