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Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography

Na(+),K(+)-ATPase transfers three Na(+) from the cytoplasm into the extracellular medium and two K(+) in the opposite direction per ATP hydrolysed. The binding and release of Na(+) and K(+) are all thought to occur sequentially. Here we demonstrate by X-ray crystallography of the ATPase in E2·MgF(4)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Ogawa, Haruo, Cornelius, Flemming, Hirata, Ayami, Toyoshima, Chikashi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918401/
https://ncbi.nlm.nih.gov/pubmed/26258479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9004
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