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Improved binding site assignment by high-resolution mapping of RNA–protein interactions using iCLIP
Individual-nucleotide resolution crosslinking and immunoprecipitation (iCLIP) allows the determination of crosslinking sites of RNA-binding proteins (RBPs) on RNAs. iCLIP is based on ultraviolet light crosslinking of RBPs to RNA, reverse transcription and high-throughput sequencing of fragments term...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918375/ https://ncbi.nlm.nih.gov/pubmed/26260686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8921 |
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