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Immunotherapy for the treatment of Alzheimer’s disease: amyloid-β or tau, which is the right target?

Alzheimer’s disease (AD) is characterized by the presence of amyloid plaques composed mainly of amyloid-β (Aβ) protein. Overproduction or slow clearance of Aβ initiates a cascade of pathologic events that may lead to formation of neurofibrillary tangles, neuronal cell death, and dementia. Although i...

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Foilsithe in:Immunotargets Ther
Main Authors: Castillo-Carranza, Diana L, Guerrero-Muñoz, Marcos J, Kayed, Rakez
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918231/
https://ncbi.nlm.nih.gov/pubmed/27471697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S40131
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