Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue

INTRODUCTION: The nicotinic α5 receptor subunit, encoded by CHRNA5, harbors multiple functional single nucleotide polymorphisms (SNPs) that affect mRNA expression and alter the encoded protein. These polymorphisms are most notably associated with drug-taking behaviors and cognition. We previously id...

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Veröffentlicht in:Genes Environ
Hauptverfasser: Ramsay, Jessica E., Rhodes, C. Harker, Thirtamara-Rajamani, Keerthi, Smith, Ryan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917931/
https://ncbi.nlm.nih.gov/pubmed/27350810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-015-0020-x
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