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Therapeutic protein–drug interaction assessment for daclizumab high‐yield process in patients with multiple sclerosis using a cocktail approach

AIMS: To characterize the potential effect of daclizumab high‐yield process (DAC HYP), a monoclonal antibody that blocks the high‐affinity interleukin‐2 receptors for treatment of multiple sclerosis, on activity of cytochrome P450 (CYP) enzymes. METHODS: Twenty patients with multiple sclerosis recei...

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Detaylı Bibliyografya
Yayımlandı:Br J Clin Pharmacol
Asıl Yazarlar: Tran, Jonathan Q., Othman, Ahmed A., Wolstencroft, Paul, Elkins, Jacob
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917816/
https://ncbi.nlm.nih.gov/pubmed/26991517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12936
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