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Pharmacokinetics of daclizumab high-yield process with repeated administration of the clinical subcutaneous regimen in patients with relapsing-remitting multiple sclerosis

BACKGROUND: Daclizumab high-yield process (DAC HYP), a humanized immunoglobulin G1 monoclonal antibody specific for the α subunit (CD25) of the high-affinity interleukin-2 receptor, has demonstrated efficacy for treatment of relapsing forms of multiple sclerosis in Phase II and III clinical trials....

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Detalhes bibliográficos
Publicado no:Clin Pharmacol
Main Authors: Tran, Jonathan Q, Othman, Ahmed A, Mikulskis, Alvydas, Wolstencroft, Paul, Elkins, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755689/
https://ncbi.nlm.nih.gov/pubmed/26929672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S98221
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