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Therapeutic protein–drug interaction assessment for daclizumab high‐yield process in patients with multiple sclerosis using a cocktail approach
AIMS: To characterize the potential effect of daclizumab high‐yield process (DAC HYP), a monoclonal antibody that blocks the high‐affinity interleukin‐2 receptors for treatment of multiple sclerosis, on activity of cytochrome P450 (CYP) enzymes. METHODS: Twenty patients with multiple sclerosis recei...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917816/ https://ncbi.nlm.nih.gov/pubmed/26991517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12936 |
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