Lipopolysaccharide-induced binding of receptor CD300b to Toll-like receptor 4 alters signaling to drive lethal cytokine responses that enhance septic shock

Receptor CD300b is implicated in regulating the immune response to bacterial infection by an unknown mechanism. Here, we identified CD300b as an lipopolysaccharide (LPS)-binding receptor and determined the mechanism underlying CD300b augmentation of septic shock. In vivo depletion and adoptive trans...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Voss, Oliver H., Murakami, Yousuke, Pena, Mirna Y., Lee, Ha-Na, Tian, Linjie, Margulies, David H., Street, Jonathan M., Yuen, Peter S. T., Qi, Chen-Feng, Krzewski, Konrad, Coligan, John E.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917413/
https://ncbi.nlm.nih.gov/pubmed/27261276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.05.005
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