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3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma

PURPOSE: Multiple myeloma (MM) is the second most prevalent hematological malignancy and it remains incurable despite the introduction of several novel drugs. The discrepancy between preclinical and clinical outcomes can be attributed to the failure of classic two-dimensional (2D) culture models to...

詳細記述

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書誌詳細
出版年:Biomaterials
主要な著者: de la Puente, Pilar, Muz, Barbara, Gilson, Rebecca C, Azab, Feda, Luderer, Micah, King, Justin, Achilefu, Samuel, Vij, Ravi, Azab, Abdel Kareem
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917006/
https://ncbi.nlm.nih.gov/pubmed/26402156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.09.017
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