3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma

PURPOSE: Multiple myeloma (MM) is the second most prevalent hematological malignancy and it remains incurable despite the introduction of several novel drugs. The discrepancy between preclinical and clinical outcomes can be attributed to the failure of classic two-dimensional (2D) culture models to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomaterials
Main Authors: de la Puente, Pilar, Muz, Barbara, Gilson, Rebecca C, Azab, Feda, Luderer, Micah, King, Justin, Achilefu, Samuel, Vij, Ravi, Azab, Abdel Kareem
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917006/
https://ncbi.nlm.nih.gov/pubmed/26402156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.09.017
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