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3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma
PURPOSE: Multiple myeloma (MM) is the second most prevalent hematological malignancy and it remains incurable despite the introduction of several novel drugs. The discrepancy between preclinical and clinical outcomes can be attributed to the failure of classic two-dimensional (2D) culture models to...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917006/ https://ncbi.nlm.nih.gov/pubmed/26402156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.09.017 |
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