High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation

In lymphatic tissues, chronic lymphocytic leukemia (CLL) cells are interspersed with CD68(+) nurselike cells (NLCs), T cells, and other stromal cells that constitute the leukemia microenvironment. However, the mechanism regulating colocalization of CLL and these accessory cells are largely unknown....

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Burger, Jan A., Quiroga, Maite P., Hartmann, Elena, Bürkle, Andrea, Wierda, William G., Keating, Michael J., Rosenwald, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916945/
https://ncbi.nlm.nih.gov/pubmed/19074730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170415
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